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Article

Integrating complement into the molecular pathogenesis of Hidradenitis Suppurativa

5 Nov 2019

Abstract excerpt

Complement inhibition has been identified as a potential therapeutic target for multiple inflammatory disorders including Hidradenitis Suppurativa (HS). It is currently unclear how complement integrates into our current model of molecular pathogenesis in HS and whether it represents a central component of pathogenesis, or a neutrophil-associated bystander. Levels of C5a in serum and tissue correlate with disease...

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PMID: 31688984
DOI: 10.1111/exd.14056

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