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Article

Familial aggregation and heritability of sarcoidosis: a Swedish nested case-control study.

The European respiratory journal - 1 Aug 2018

Rossides Marios, Grunewald Johan, Eklund Anders, Kullberg Susanna, Di Giuseppe Daniela, Askling Johan, Arkema Elizabeth V

Abstract excerpt

Sarcoidosis is believed to be caused by both genetic and environmental risk factors, but the proportion of the susceptibility to sarcoidosis that is mediated by genetics remains unknown. We aimed to estimate the familial aggregation and heritability of sarcoidosis using a case-control-family study design and population-based Swedish registers.We identified 23 880 individuals with visits for sarcoidosis in the...

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PMID: 29946010
DOI: 10.1183/13993003.00385-2018

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