Article
Familial aggregation of rheumatoid arthritis and co-aggregation of autoimmune diseases in affected families: a nationwide population-based study.
Rheumatology (Oxford, England) - 1 Jun 2017
Kuo Chang-Fu, Grainge Matthew J, Valdes Ana M, See Lai-Chu, Yu Kuang-Hui, Shaw S W Steven, Luo Shue-Fen, Zhang Weiya, Doherty Michael
Abstract excerpt
Objective: The aim was to estimate familial relative risk (RR) for RA and other autoimmune diseases and the genetic contribution to RA phenotypic variance (heritability). Methods: This study used the Taiwan National Health Insurance Research Database to identify all National Health Insurance registered beneficiaries (n = 23 658 577) in 2010; among them, 37 482 individuals had RA. We estimated familial RRs and 95%...
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