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Article

Familial aggregation and heritability: a nationwide family-based study of idiopathic inflammatory myopathies.

Annals of the rheumatic diseases - 1 Nov 2021

Che Weng Ian, Westerlind Helga, Lundberg Ingrid E, Hellgren Karin, Kuja-Halkola Ralf, Holmqvist Marie

Abstract excerpt

OBJECTIVES: The magnitude of the genetic contribution to idiopathic inflammatory myopathies (IIMs) is unknown. In this project, we aimed to investigate the familial aggregation and heritability of IIM. METHODS: This is a family-based study using nationwide healthcare register data in Sweden. We matched each patient with IIM to individuals without IIM, identified their first-degree relatives and determined the IIM...

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Identifiers

PMID: 34130985
DOI: 10.1136/annrheumdis-2021-219914
PMCID: PMC8522465

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