Subtype-Based Prognostic Analysis of Cell-in-Cell Structures in Early Breast Cancer

Abstract excerpt

Though current pathological methods are greatly improved, they provide rather limited functional information. Cell-in-cell structures (CICs), arising from active cell-cell interaction, are functional surrogates of complicated cell behaviors within heterogeneous cancers. In light of this, we performed the first subtype-based CICs profiling in human breast cancers by “EML” multiplex staining method, and accessed...

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