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Article

Reducing cardiovascular risk in patients with familial hypercholesterolemia: Risk prediction and lipid management.

Progress in cardiovascular diseases - 1 Jan 2000

Miname Marcio H, Santos Raul D

Abstract excerpt

Familial hypercholesterolemia (FH) is a frequent genetic disorder characterized by elevated low-density lipoprotein (LDL)-cholesterol (LDL-C) levels and early onset of atherosclerotic cardiovascular disease. FH is caused by mutations in genes that regulate LDL catabolism, mainly the LDL receptor (LDLR), apolipoprotein B (APOB) and gain of function of proprotein convertase subtilisin kexin type 9 (PCSK9). However,...

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Identifiers

PMID: 31669498
DOI: 10.1016/j.pcad.2019.10.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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