Article
Glucose and glutamine metabolism in relation to mutational status in NSCLC histological subtypes.
Thoracic cancer - 1 Dec 2019
Meijer Tineke W H, Looijen-Salamon Monika G, Lok Jasper, van den Heuvel Michel, Tops Bastiaan, Kaanders Johannes H A M, Span Paul N, Bussink Johan
Abstract excerpt
BACKGROUND: Both hypoxia and oncogenic mutations rewire tumor metabolism. In this study, glucose and glutamine metabolism-related markers were examined in stage I - resectable stage IIIA non-small cell lung cancer (NSCLC). Furthermore, expression of metabolism-related markers was correlated with mutational status to examine mutations associated with rewired tumor metabolism. METHODS: Mutation analysis was...
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