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Article

FAM20A is essential for amelogenesis, but is dispensable for dentinogenesis.

Journal of molecular histology - 1 Dec 2019

Li Lili, Saiyin Wuliji, Zhang Hua, Wang Suzhen, Xu Qian, Qin Chunlin, Lu Yongbo

Abstract excerpt

Mutations in the gene encoding family with sequence similarity 20, member A (FAM20A) caused amelogenesis imperfecta (AI), in humans. However, the roles of FAM20A in amelogenesis and dentinogenesis are poorly understood. In this study, we generated a Fam20a knockout (Sox2-Cre;Fam20afl/fl) mouse model by crossing Fam20afl/fl mice with Sox2-Cre transgenic mice, in which Fam20a was ablated in both dental epithelium...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31667691
DOI: 10.1007/s10735-019-09851-x
PMCID: PMC6861166

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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