Article
Expansion of natural killer cells in patients with head and neck cancer: detection of "noninhibitory" (activating) killer Ig-like receptors on circulating natural killer cells.
Head & neck - 1 Apr 2003
Melioli Giovanni, Semino Claudia, Margarino Giovanni, Mereu Paola, Scala Marco, Cangemi Giuliana, Crocetti Emanuele, Machì Anna Maria, Ferlazzo Guido
Abstract excerpt
BACKGROUND: In a group of patients with head and neck cancers (H&NC), the expansion of the population of CD3-,CD16+ natural killer (NK) cells in the peripheral blood was studied. METHODS: Cytofluorimetric analysis of the expression of killer Ig-like receptors (KIR, namely p58.1, p58.2, p58.3, p70, and p140) and CD94-NKG2a was performed. Cytolytic activities were studied using 51Cr release assay. T and NK cell...
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