Article
Hash-Based Core Genome Multilocus Sequence Typing for Clostridium difficile.
Journal of clinical microbiology - 23 Dec 2019
Eyre David W, Peto Tim E A, Crook Derrick W, Walker A Sarah, Wilcox Mark H
Abstract excerpt
Pathogen whole-genome sequencing has huge potential as a tool to better understand infection transmission. However, rapidly identifying closely related genomes among a background of thousands of other genomes is challenging. Here, we describe a refinement to core genome multilocus sequence typing (cgMLST) in which alleles at each gene are reproducibly converted to a unique hash, or short string of letters...
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