Using multilocus sequence typing to study bacterial variation: prospects in the genomic era.

doi:10.2217/fmb.14.24

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Article

Using multilocus sequence typing to study bacterial variation: prospects in the genomic era.

Future microbiology - 1 Jan 2014

Jolley Keith A, Maiden Martin C J

Abstract excerpt

Multilocus sequence typing (MLST) indexes the sequence variation present in a small number (usually seven) of housekeeping gene fragments located around the bacterial genome. Unique alleles at these loci are assigned arbitrary integer identifiers, which effectively summarizes the variation present in several thousand base pairs of genome sequence information as a series of numbers. Comparing bacterial isolates...

Topics

Bacillus anthracis
Bacterial Typing Techniques
Base Sequence
Biodiversity
Genetic Variation
Genome, Bacterial
Microbial Sensitivity Tests
Multilocus Sequence Typing
Neisseria meningitidis
Pseudomonas aeruginosa
Sequence Analysis, DNA

Source

Open in PubMed

Identifiers

PMID: 24957089
DOI: 10.2217/fmb.14.24

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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