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Article

Fourteen-genome comparison identifies DNA markers for severe-disease-associated strains of Clostridium difficile.

Journal of clinical microbiology - 1 Jun 2011

Forgetta Vincenzo, Oughton Matthew T, Marquis Pascale, Brukner Ivan, Blanchette Ruth, Haub Kevin, Magrini Vince, Mardis Elaine R, Gerding Dale N, Loo Vivian G, Miller Mark A, Mulvey Michael R, Rupnik Maja, Dascal Andre, Dewar Ken

Abstract excerpt

Clostridium difficile is a common cause of infectious diarrhea in hospitalized patients. A severe and increased incidence of C. difficile infection (CDI) is associated predominantly with the NAP1 strain; however, the existence of other severe-disease-associated (SDA) strains and the extensive genetic diversity across C. difficile complicate reliable detection and diagnosis. Comparative genome analysis of 14...

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Identifiers

PMID: 21508155
DOI: 10.1128/JCM.00391-11
PMCID: PMC3122728

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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