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Antibiotic Bacillomycin D Affects Iron Acquisition and Biofilm Formation in Bacillus velezensis through a Btr-Mediated FeuABC-Dependent Pathway.

Cell reports - 29 Oct 2019

Xu Zhihui, Mandic-Mulec Ines, Zhang Huihui, Liu Yan, Sun Xinli, Feng Haichao, Xun Weibing, Zhang Nan, Shen Qirong, Zhang Ruifu

Abstract excerpt

Bacillus spp. produce a wide range of secondary metabolites, including antibiotics, which have been well studied for their antibacterial properties but less so as signaling molecules. Previous results indicated that the lipopeptide bacillomycin D is a signal that promotes biofilm development of Bacillus velezensis SQR9. However, the mechanism behind this signaling is still unknown. Here, we show that bacillomycin...

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PMID: 31665633
DOI: 10.1016/j.celrep.2019.09.061

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