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Physiological and transcriptional profiling of surfactin exerted antifungal effect against Candida albicans

3 Jun 2022

Abstract excerpt

Given the risk of Candida albicans overgrowth in the gut, novel complementary therapies should be developed to reduce fungal dominancy. This study highlights the antifungal characteristics of a Bacillus subtilis-derived secondary metabolite, surfactin with high potential against C. albicans. Surfactin inhibited the growth of C. albicans following a 1-hour exposure, in addition to reduced adhesion and...

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PMID: 35671583
DOI: 10.1016/j.biopha.2022.113220

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