Mitigating Candida albicans virulence by targeted relay of pulcherriminic acid during antagonistic biofilm formation by Bacillus subtilis

Abstract excerpt

The antagonistic biofilms formed by probiotic Bacilli may significantly mitigate persistent strains of Candida albicans , which are often involved in severe oral, vulvovaginal or systemic infections in humans. Here, we report on a spatiotemporal antagonistic activity mediated through pulcherriminic acid (PA) production by biofilm-forming B. subtilis , which is subsequently transported to the extracellular...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Antifungal resistance and susceptibility
• Share to Bacterial biofilms and quorum sensing
• Share to Probiotics and Fermented Foods