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Article

Dysregulation of Placental Functions and Immune Pathways in Complete Hydatidiform Moles

10 Oct 2019

Abstract excerpt

Gene expression studies of molar pregnancy have been limited to a small number of candidate loci. We analyzed high-dimensional RNA and protein data to characterize molecular features of complete hydatidiform moles (CHMs) and corresponding pathologic pathways. CHMs and first trimester placentas were collected, histopathologically examined, then flash-frozen or paraffin-embedded. Frozen CHMs and control placentas...

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PMID: 31658584
DOI: 10.3390/ijms20204999

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