Article
Hydatidiform Moles: Genetic Basis and Precision Diagnosis.
Annual review of pathology - 24 Jan 2017
Hui Pei, Buza Natalia, Murphy Kathleen M, Ronnett Brigitte M
Abstract excerpt
Hydatidiform moles are intriguing pathologic entities representing abnormal placental villous tissue with unique genetic profiles and a wide spectrum of morphologic features, which makes accurate diagnosis challenging. Overrepresentation of the paternal genome in sporadic hydatidiform moles (purely androgenetic in complete hydatidiform moles and diandric triploid in partial hydatidiform moles) is a fundamental...
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