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Article

Genetic codes optimized as a traveling salesman problem.

PloS one - 1 Jan 2019

Attie Oliver, Sulkow Brian, Di Chong, Qiu Weigang

Abstract excerpt

The Standard Genetic Code (SGC) is robust to mutational errors such that frequently occurring mutations minimally alter the physio-chemistry of amino acids. The apparent correlation between the evolutionary distances among codons and the physio-chemical distances among their cognate amino acids suggests an early co-diversification between the codons and amino acids. Here we formulated the co-minimization of...

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Identifiers

PMID: 31658301
DOI: 10.1371/journal.pone.0224552
PMCID: PMC6816573

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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