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Article

Increased expression of TET3 predicts unfavorable prognosis in patients with ovarian cancer-a bioinformatics integrative analysis.

Journal of ovarian research - 27 Oct 2019

Cao Tiefeng, Pan Wenwei, Sun Xiaoli, Shen Huimin

Abstract excerpt

Ovarian carcinoma is a lethal gynecological malignancy. Women with ovarian cancer (OC) are highly recurrent and typically diagnosed at late stage. Ten-eleven translocation protein 3 (TET3) belongs to the family of ten-eleven translocations (TETs) which induce DNA demethylation and gene regulation in epigenetic level by converting 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC). Previous studies indicated...

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Identifiers

PMID: 31656201
DOI: 10.1186/s13048-019-0575-4
PMCID: PMC6816171

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