Article
Association of Mouse Double Minute 2 -309T>G Polymorphism with Acute Myeloid Leukemia in an Iranian Population: A Case- Control Study.
Asian Pacific journal of cancer prevention : APJCP - 1 Oct 2019
Soleymannejad Mona, Sheikhha Mohammad Hassan, Neamatzadeh Hossein
Abstract excerpt
BACKGROUND: Genetic factors play a substantial role in acute myeloid leukemia (AML) etiology. Overexpression of the mouse double minute 2 (MDM2) gene has been explored in many tumors. However, the role of MDM2 -309T>G (rs2279744) polymorphism in AML remains unclear. We have performed this study to examine the association of MDM2 -309T>G with AML in an Iranian population. METHODS: We have examined the association...
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