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Article

An integration-free iPSC line (SDQLCHi012-A) derived from a patient with inflammatory bowel disease- 28 carrying compound heterozygote mutations in IL10RA gene.

Stem cell research - 1 Dec 2019

Ma Yanyan, Zhang Haiyan, Zhang Shisong, Dong Rui, Yang Xiaomeng, Li Yue, Guan Jingyun, Gai Zhongtao, Liu Yi

Abstract excerpt

Induced pluripotent stem cell (iPSC) line (SDQLCHi012-A) was generated from peripheral blood mononuclear cells of an 11-month-old male who was diagnosed as inflammatory bowel disease-28 caused by compound heterozygote for IL10RA mutations (c.188 + 1G > A and c.301C > T). Non-integrating episomal vectors coding OCT4, SOX2, KLF4, BCL-XL and MYC were used for reprogramming. The established iPSC line contained the...

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Identifiers

PMID: 31648101
DOI: 10.1016/j.scr.2019.101577

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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