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Article

Pluronic gel-based burrowing assay for rapid assessment of neuromuscular health in C. elegans.

Scientific reports - 23 Oct 2019

Lesanpezeshki Leila, Hewitt Jennifer E, Laranjeiro Ricardo, Antebi Adam, Driscoll Monica, Szewczyk Nathaniel J, Blawzdziewicz Jerzy, Lacerda Carla M R, Vanapalli Siva A

Abstract excerpt

Whole-organism phenotypic assays are central to the assessment of neuromuscular function and health in model organisms such as the nematode C. elegans. In this study, we report a new assay format for engaging C. elegans in burrowing that enables rapid assessment of nematode neuromuscular health. In contrast to agar environments that pose specific drawbacks for characterization of C. elegans burrowing ability,...

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Identifiers

PMID: 31645584
DOI: 10.1038/s41598-019-51608-9
PMCID: PMC6811592

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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