Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Surfeit 4 Contributes to the Replication of Hepatitis C Virus Using Double-Membrane Vesicles.

Journal of virology - 6 Jan 2020

Kong Lingbao, Aoyagi Haruyo, Yang Zibing, Ouyang Tao, Matsuda Mami, Fujimoto Akira, Watashi Koichi, Suzuki Ryosuke, Arita Minetaro, Yamagoe Satoshi, Dohmae Naoshi, Suzuki Takehiro, Suzuki Tetsuro, Muramatsu Masamichi, Wakita Takaji, Aizaki Hideki

Abstract excerpt

A number of positive-strand RNA viruses, such as hepatitis C virus (HCV) and poliovirus, use double-membrane vesicles (DMVs) as replication sites. However, the role of cellular proteins in DMV formation during virus replication is poorly understood. HCV NS4B protein induces the formation of a "membranous web" structure that provides a platform for the assembly of viral replication complexes. Our previous screen...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line, Tumor
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepacivirus

Share to Hepatitis C virus research

Share to Membrane Proteins

Share to RNA, Viral

Share to Viral Nonstructural Proteins

Share to Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 31645450
DOI: 10.1128/JVI.00858-19
PMCID: PMC6955281

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Surfeit 4 Contributes to the Replication of Hepatitis C Virus Using Double-Membrane Vesicles.PMID 31645450Read ↗

Dengue Virus- and Hepatitis C Virus-Induced Replication and Assembly Compartments: the Enemy Inside—Caught in the WebSemantic proximity Read ↗

Affinity Purification of the Hepatitis C Virus Replicase Identifies Valosin-Containing Protein, a Member of the ATPases Associated with Diverse Cellular Activities Family, as an Active Virus Replication ModulatorSemantic proximity Read ↗

Oxysterol-binding protein is a phosphatidylinositol 4-kinase effector required for HCV replication membrane integrity and cholesterol trafficking.Semantic proximity Read ↗

The roles of HCV core protein and its binding host factor in virus assembly and releaseSemantic proximity Read ↗

The Hepatitis C Virus-Induced Membranous Web and Associated Nuclear Transport Machinery Limit Access of Pattern Recognition Receptors to Viral Replication SitesSemantic proximity Read ↗

Cellular and molecular biology of HCV infection and hepatitisSemantic proximity Read ↗

Integrative Functional Genomics of Hepatitis C Virus Infection Identifies Host Dependencies in Complete Viral Replication CycleSemantic proximity Read ↗

Y-Box-Binding Protein 1 Interacts with Hepatitis C Virus NS3/4A and Influences the Equilibrium between Viral RNA Replication and Infectious Particle ProductionSemantic proximity Read ↗

The Biogenesis of Dengue Virus Replication Organelles Requires the ATPase Activity of Valosin-Containing ProteinSemantic proximity Read ↗

The Role of the RNA-RNA Interactome in the Hepatitis C Virus Life CycleSemantic proximity Read ↗

NS4B self-interaction through conserved C-terminal elements is required for the establishment of functional hepatitis C virus replication complexes.Semantic proximity Read ↗

Determinants in Nonstructural Protein 4A of Dengue Virus Required for RNA Replication and Replication Organelle Biogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.