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Article

Effects of sclerostin on lipopolysaccharide-induced inflammatory phenotype in human odontoblasts and dental pulp cells.

The international journal of biochemistry & cell biology - 1 Dec 2019

Liao Chufang, Wang Yining, Ou Yanjing, Wu Yun, Zhou Yi, Liang Shanshan

Abstract excerpt

Previously we have demonstrated that sclerostin inhibits stress-induced odontogenic differentiation of odontoblasts and accelerates senescence of dental pulp cells (DPCs) Odontoblasts and DPCs are main functioning cells for inflammation resistance and tissue regeneration in dentine-pulp complex. Sclerostin is relevant for systemic inflammation and chronic periodontitis processes, but its effects on dental pulp...

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Source

Identifiers

PMID: 31639458
DOI: 10.1016/j.biocel.2019.105628

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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