Article
Early nutrition in combination with polymorphisms in fatty acid desaturase gene cluster modulate fatty acid composition of cheek cells' glycerophospholipids in school-age children.
The British journal of nutrition - 1 Sept 2019
Martínez-Zaldívar Cristina, Azaryah Hatim, García-Santos José A, Demmelmair Hans, Altmäe Signe, Reischl Eva, Rzehak Peter, Koletzko Berthold, Campoy Cristina
Abstract excerpt
Variants in the human genes of fatty acid (FA) desaturase 1 (FADS1), 2 (FADS2) and 3 (FADS3) are associated with PUFA blood levels. We explored if maternal prenatal supplementation and children's genetic variation in seventeen SNP of the FADS1, FADS2 and FADS3 gene cluster influence twenty-one of the most relevant cheek cells' derived FA in glycerophospholipids (GPL-FA). The study was conducted in 147 Spanish and...
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