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Article

VCP/p97 Is a Proviral Host Factor for Replication of Chikungunya Virus and Other Alphaviruses

24 Sept 2019

Abstract excerpt

The evolutionarily conserved AAA+ ATPase Valosin-Containing Protein (VCP) was previously shown to be a proviral host factor for several viruses from different viral families such as Flaviviridae, Picornaviridae and Herpesviridae. VCP was shown to affect trafficking of Sindbis virus receptor and functions as a component of Semliki Forest virus (SFV) replicase compartment. However, the role of this cellular protein...

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PMID: 31636613
DOI: 10.3389/fmicb.2019.02236

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