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Insights into replicative senescence of human testicular peritubular cells

21 Oct 2019

Abstract excerpt

There is evidence for an age-related decline in male reproductive functions, yet how the human testis may age is not understood. Human testicular peritubular cells (HTPCs) transport sperm, contribute to the spermatogonial stem cell (SSC) niche and immune surveillance, and can be isolated and studied in vitro. Consequences of replicative senescence of HTPCs were evaluated to gain partial insights into human...

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PMID: 31636313
DOI: 10.1038/s41598-019-51380-w

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