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The Molecular Signature of Human Testicular Peritubular Cells Revealed by Single-Cell Analysis

19 Nov 2022

Abstract excerpt

Peritubular cells of the human testis form a small compartment surrounding the seminiferous tubules. They are crucial for sperm transport, and they emerge as contributors to the spermatogonial stem cell niche. They are among the least known cell types of the human body. We employed single-cell RNA sequencing of cultured human testicular peritubular cells (HTPCs), which had been isolated from testicular samples of...

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PMID: 36429113
DOI: 10.3390/cells11223685

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