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Microsatellite Instability assessment in Black South African Colorectal Cancer patients reveal an increased incidence of suspected Lynch syndrome

21 Oct 2019

Abstract excerpt

Microsatellite Instability (MSI) is a hallmark of colorectal cancer (CRC) and occurs in 15-16% of CRC. Molecular biological information of CRC in South Africa (SA) is largely unrecorded. This study was undertaken to determine the frequency of MSI, with particular reference to Lynch syndrome (LS) with a view to improve surveillance and prevention strategies. This was a retrospective study on CRC samples diagnosed...

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PMID: 31636305
DOI: 10.1038/s41598-019-51316-4

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