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Escherichia coli Global Gene Expression in Urine from Women with Urinary Tract Infection

11 Nov 2010

Abstract excerpt

Murine models of urinary tract infection (UTI) have provided substantial data identifying uropathogenic E. coli (UPEC) virulence factors and assessing their expression in vivo. However, it is unclear how gene expression in these animal models compares to UPEC gene expression during UTI in humans. To address this, we used a UPEC strain CFT073-specific microarray to measure global gene expression in eight E. coli...

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PMID: 21085611
DOI: 10.1371/journal.ppat.1001187

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