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Host-specific induction of <i>Escherichia coli</i> fitness genes during human urinary tract infection

8 Dec 2014

Abstract excerpt

Uropathogenic Escherichia coli (UPEC) is the predominant etiological agent of uncomplicated urinary tract infection (UTI), manifested by inflammation of the urinary bladder, in humans and is a major global public health concern. Molecular pathogenesis of UPEC has been primarily examined using murine models of UTI. Translational research to develop novel therapeutics against this major pathogen, which is becoming...

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PMID: 25489107
DOI: 10.1073/pnas.1415959112

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