The Implicated Roles of Cell Adhesion Molecule 1 (CADM1) Gene and Altered Prefrontal Neuronal Activity in Attention-Deficit/Hyperactivity Disorder: A “Gene–Brain–Behavior Relationship”?

Abstract excerpt

Background: Genes related to cell adhesion pathway have been implicated in the genetic architecture of Attention-Deficit/Hyperactivity Disorder (ADHD). Cell adhesion molecule 1, encoded by CADM1 gene, is a protein facilitating cell adhesion, highly expressed in the human prefrontal lobe. This study aimed to evaluate the association of CADM1 genotype with ADHD, executive function, and regional brain functions....

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