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Article

Identification of NTRK3 as a potential prognostic biomarker associated with tumor mutation burden and immune infiltration in bladder cancer.

BMC cancer - 24 Apr 2021

Zhang Zhao, Yu Yongbo, Zhang Pengfei, Ma Guofeng, Zhang Mingxin, Liang Ye, Jiao Wei, Niu Haitao

Abstract excerpt

BACKGROUND: Bladder cancer (BLCA) is a common malignant tumor of urinary system with high morbidity and mortality. In recent years, immunotherapy has played a significant role in the treatment of BLCA. Tumor mutation burden (TMB) has been reported to be a powerful biomarker for predicting tumor prognosis and efficacy of immunotherapy. Our study aimed to explore the relationship between TMB, prognosis and immune...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33894748
DOI: 10.1186/s12885-021-08229-1
PMCID: PMC8070296

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