Article
Identification of gene expression profiles and immune cell infiltration signatures between low and high tumor mutation burden groups in bladder cancer.
International journal of medical sciences - 1 Jan 2020
Wu Zonglong, Wang Muru, Liu Qinggang, Liu Yaxiao, Zhu Kejia, Chen Lipeng, Guo Hongda, Li Yan, Shi Benkang
Abstract excerpt
Bladder cancer is one of the most commonly diagnosed tumors and is results from the accumulation of somatic mutations in the DNA. Tumor mutation burden (TMB) has been associated with cancer immunotherapeutic response. In this study, we attempted to explore the correlation between TMB and cancer prognosis. Identify the different expressed genes and immune cell infiltration signatures between low and high TMB...
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