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Article

Immunohistochemical Toolkit for Tracking and Quantifying Xenotransplanted Human Stem Cells

1 Jul 2014

Abstract excerpt

AIM: Biomarker-based tracking of human stem cells xenotransplanted into animal models is crucial for studying their fate in the field of cell therapy or tumor xenografting. MATERIALS & METHODS: Using immunohistochemistry and in situ hybridization, we analyzed the expression of three human-specific biomarkers: Ku80, human mitochondria (hMito) and Alu. RESULTS: We showed that Ku80, hMito and Alu biomarkers are...

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PMID: 25159062
DOI: 10.2217/rme.14.26

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