Article
Cerebrospinal fluid biomarkers in human genetic transmissible spongiform encephalopathies.
Journal of neurology - 1 Oct 2009
Ladogana Anna, Sanchez-Juan Pascual, Mitrová Eva, Green Alison, Cuadrado-Corrales Natividad, Sánchez-Valle Raquel, Koscova Silvia, Aguzzi Adriano, Sklaviadis Theodoros, Kulczycki Jerzy, Gawinecka Joanna, Saiz Albert, Calero Miguel, van Duijn Cornelia M, Pocchiari Maurizio, Knight Richard, Zerr Inga
Abstract excerpt
The 14-3-3 protein test has been shown to support the clinical diagnosis of sporadic Creutzfeldt-Jakob disease (CJD) when associated with an adequate clinical context, and a high differential potential for the diagnosis of sporadic CJD has been attributed to other cerebrospinal fluid (CSF) proteins such as tau protein, S100b and neuron specific enolase (NSE). So far there has been only limited information...
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