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Comparison of BEAMing and Droplet Digital PCR for Circulating Tumor DNA Analysis

24 Sept 2019

Abstract excerpt

Abstract BACKGROUND Circulating tumor DNA (ctDNA) assays are increasingly used for clinical decision-making, but it is unknown how well different assays agree. We aimed to assess the agreement in ctDNA mutation calling between BEAMing (beads, emulsion, amplification, and magnetics) and droplet digital PCR (ddPCR), 2 of the most commonly used digital PCR techniques for detecting mutations in ctDNA. METHODS...

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PMID: 31551314
DOI: 10.1373/clinchem.2019.305805

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