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Article

CRY2 suppresses trophoblast migration and invasion in recurrent spontaneous abortion

16 Sept 2019

Abstract excerpt

Disruption of circadian rhythms is associated with aberrant trophoblast migration and invasion in recurrent spontaneous abortion (RSA). This study aims to explore the functional role and the mechanisms of cryptochrome 2 (CRY2), a fundamental component of the circadian clock, in regulating trophoblast migration and invasion. Human extravillous trophoblast cell line HTR-8/SVneo was used as a cell model. Cell...

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PMID: 31536114
DOI: 10.1093/jb/mvz076

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