Modeling human ectopic pregnancies with trophoblast and vascular organoids

Abstract excerpt

Ruptured ectopic pregnancy (REP), a pregnancy complication caused by aberrant implantation, deep invasion, and overgrowth of embryos in fallopian tubes, could lead to rupture of fallopian tubes and accounts for 4%-10% of pregnancy-related deaths. The lack of ectopic pregnancy phenotypes in rodents hampers our understanding of its pathological mechanisms. Here, we employed cell culture and organoid models to...

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• Share to Ectopic Pregnancy Diagnosis and Management
• Share to Pregnancy and preeclampsia studies
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