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High‐Throughput Gene Replacement in Aspergillus fumigatus

7 Aug 2019

Abstract excerpt

Aspergillus fumigatus is a human pathogen and the principal etiologic agent of invasive and chronic aspergillosis leading to several hundreds of thousands of deaths every year. Very few antifungals are available to treat infections caused by A. fumigatus, and resistance is developing to those we have. Our understanding of the molecular mechanisms that drive pathogenicity and drug resistance have been hampered by...

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PMID: 31518064
DOI: 10.1002/cpmc.88

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