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Article

Human cardiac myosin light chain 4 (MYL4) mosaic expression patterns vary by sex

3 Sept 2019

Abstract excerpt

Sex disparities modulate cardiac function, although the proteins and mechanisms remain to be elucidated. We recently demonstrated a mosaic pattern of protein expression in the heart for over 100 proteins. Here we investigate one of these proteins, myosin light chain 4 (MYL4), which is important for contractile functions by increasing force production. We assayed the expression pattern of MYL4 across 756...

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PMID: 31481666
DOI: 10.1038/s41598-019-49191-0

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