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Article

Effect of Systolic Blood Pressure on Left Ventricular Structure and Function

3 Sept 2019

Abstract excerpt

We aimed to estimate the effects of a lifelong exposure to high systolic blood pressure (SBP) on left ventricular (LV) structure and function using Mendelian randomization. A total of 5596 participants of the UK Biobank were included for whom cardiovascular magnetic resonance imaging and genetic data were available. Major exclusion criteria included nonwhite ethnicity, major cardiovascular disease, and body mass...

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PMID: 31476911
DOI: 10.1161/hypertensionaha.119.12679

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