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Article

Individual Effector/Regulator T Cell Ratios Impact Bone Regeneration

16 Aug 2019

Abstract excerpt

There is increasing evidence that T lymphocytes play a key role in controlling endogenous regeneration. Regeneration appears to be impaired in case of local accumulation of CD8+ effector T cells (TEFF), impairing endogenous regeneration by increasing a primary “useful” inflammation towards a damaging level. Thus, rescuing regeneration by regulating the heightened pro-inflammatory reaction employing regulatory...

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PMID: 31475013
DOI: 10.3389/fimmu.2019.01954

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