Many Faces of Regulatory T Cells: Heterogeneity or Plasticity?

Abstract excerpt

Regulatory T cells (Tregs) are essential for maintaining the immune balance in normal and pathological conditions. In autoimmune diseases and transplantation, they restrain the loss of self-tolerance and promote engraftment, whereas in cancer, an increase in Treg numbers is mostly associated with tumor growth and poor prognosis. Numerous markers and their combinations have been used to identify Treg subsets,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cell Plasticity
• Share to Neoplasms
• Share to Phenotype