Article
Population Variability Generated during Rescue Process and Passaging of Recombinant Mumps Viruses.
Viruses - 20 Dec 2021
Slović Anamarija, Košutić-Gulija Tanja, Forčić Dubravko, Šantak Maja, Jagušić Maja, Jurković Mirna, Pali Dorotea, Ivančić-Jelečki Jelena
Abstract excerpt
Recombinant mumps viruses (MuVs) based on established vaccine strains represent attractive vector candidates as they have known track records for high efficacy and the viral genome does not integrate in the host cells. We developed a rescue system based on the consensus sequence of the L-Zagreb vaccine and generated seven different recombinant MuVs by (a) insertion of one or two additional transcription units...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
