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Genetic and biological characterisation of Zika virus isolates from different Brazilian regions

1 Jan 2019

Abstract excerpt

BACKGROUND: Zika virus (ZIKV) infections reported in recent epidemics have been linked to clinical complications that had never been associated with ZIKV before. Adaptive mutations could have contributed to the successful emergence of ZIKV as a global health threat to a nonimmune population. However, the causal relationships between the ZIKV genetic determinants, the pathogenesis and the rapid spread in Latin...

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PMID: 31432892
DOI: 10.1590/0074-02760190150

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