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African and Asian Zika Virus Isolates Display Phenotypic Differences Both In Vitro and In Vivo

27 Dec 2017

Abstract excerpt

Zika virus (ZIKV) is a mosquito-borne member of the genus Flavivirus that has emerged since 2007 to cause outbreaks in Africa, Asia, Oceania, and most recently, in the Americas. Here, we used an isolate history as well as genetic and phylogenetic analyses to characterize three low-passage isolates representing African (ArD 41525) and Asian (CPC-0740, SV0127-14) lineages to investigate the potential phenotypic...

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PMID: 29280428
DOI: 10.4269/ajtmh.17-0685

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