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Article

Integrating multiomics longitudinal data to reconstruct networks underlying lung development

21 Aug 2019

Abstract excerpt

A comprehensive understanding of the dynamic regulatory networks that govern postnatal alveolar lung development is still lacking. To construct such a model, we profiled mRNA, microRNA, DNA methylation, and proteomics of developing murine alveoli isolated by laser capture microdissection at 14 predetermined time points. We developed a detailed comprehensive and interactive model that provides information about...

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PMID: 31432713
DOI: 10.1152/ajplung.00554.2018

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