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Endometriosis and Ovarian Cancer: Insights from NHANES and Mendelian Randomization Analysis.

Reproductive sciences (Thousand Oaks, Calif.) - 1 Jul 2025

Liu Dong, Wu Yuke, Zhou Kunyan

Abstract excerpt

Endometriosis describes the growth of extra-uterine endometrium, causing pain and inflammation, and the condition has been estimated to affect 10% of women of reproductive age. It remains under-diagnosed and has been linked to increased cancer risk. This study evaluated the correlation between endometriosis and cancer. The significance of specific loci to cancer was analyzed via Mendelian randomization (MR). Of...

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Identifiers

PMID: 40550987
DOI: 10.1007/s43032-025-01910-x
PMCID: PMC12270951

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