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Article

Transcriptional Regulation of Autophagy: Mechanisms and Diseases

2 Jul 2019

Abstract excerpt

Macro (Autophagy) is a catabolic process that relies on the cooperative function of two organelles: the lysosome and the autophagosome. The recent discovery of a transcriptional gene network that co-regulates the biogenesis and function of these two organelles, and the identification of transcription factors, miRNAs and epigenetic regulators of autophagy, demonstrated that this catabolic process is controlled by...

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PMID: 31312633
DOI: 10.3389/fcell.2019.00114

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